(+)-JQ-1 AS A BET INHIBITOR SECRETS

In truth, TERT phosphorylation has long been demonstrated for being needed for telomerase activation. b Effect of BETi on telomere regulation. BETi compete with acetylated histones with the binding for the BRD4 bromodomains releasing BRD4 from limited telomere, destabilizing telomere security advanced Firm and decreasing Telomerase activity. The pr